关于HILICON
HILIC概念最早由Andrew Alpert于1990年提出，旨在解决传统反相色谱（RPLC）对强极性化合物（如糖类、肽类、核酸等）分离效率低的问题。早期采用高比例有机相（如乙腈/水）作为流动相，结合硅胶或氨基键合固定相，通过亲水相互作用实现分离。随着新型固定相材料（如两性离子硅胶、聚合物基质）和仪器技术（如高精度泵、质谱联用）的发展，HILIC方法的重复性和适用范围显著提升。HILIC与高分辨质谱（HRMS）联用成为主流，推动其在复杂生物样本（如血浆、尿液）和外源性物（如药物代谢物、环境污染物）分析中的应用。如今，HILIC已应用广泛于生物样本分析、临床诊断、天然产物与药物开发、食品与食品安全、环境监测和制药工业
品牌故事：在与HILICON创始人的讨论时，我们被他始终如一的坚持和创新精神所感染。与伙伴们成功创立并售出Sequent® Zic-Hilic®后，创立HILICON，改进创新推出新的两性离子型亲水作用色谱柱系列iHILIC®-（P）Classic、iHILIC®-Fusion、iHILIC®-Fusion(P)、iHILIC®-Fusion(+)及iSPE®-HILIC前处理小柱系列，并迅速应用于血液和粪便代谢组学、蛋白组学、临床诊断生物标志物检测、天然产物中的极性成分分离、手性药物分离、食品中的极性成分和农药残留检测、水/土壤/沉积物中的极性和亲水性有机污染物检测、单克隆抗体的糖基化分析等领域。
iHILIC®-(P) Classic 色谱柱
iHILIC色谱柱专为通过亲水作用液相色谱法（HILIC）分离和纯化极性及亲水性化合物而设计。其填充固定相采用两性离子型电荷修饰的酰胺硅胶或聚合物颗粒，这些基质通过共价键合中性、正电荷及负电荷的亲水功能基团。因此，iHILIC色谱柱的分离机制基于亲水作用、氢键作用和弱静电相互作用的协同效应，具有独特的分离选择性和高分离效率。
iHILIC色谱柱提供四种不同的表面化学特性，可提供互补的选择性以满足多样化分析需求。
产品分类
iHILIC®-(P) Classic 色谱柱系列，是电荷修饰的二醇基HILIC色谱柱：
|
P/N |
Product Name |
|
160.022.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,20x2.1mm,5µm,200Å |
|
160.032.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,30x2.1mm,5µm,200Å |
|
160.052.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,50x2.1mm,5µm,200Å |
|
160.102.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,100x2.1mm,5µm,200Å |
|
160.152.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,150x2.1mm,5µm,200Å |
|
160.252.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,250x2.1mm,5µm,200Å |
|
160.054.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,50x4.6mm,5µm,200Å |
|
160.104.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,100x4.6mm,5µm,200Å |
|
160.154.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,150x4.6mm,5µm,200Å |
|
160.254.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK,250x4.6mm,5µm,200Å |
|
161.122.0520 |
iHILIC®-(P) Classic,Guard Column,PEEK,20x2.1mm,5µm,200Å,1pk |
|
161.322.0520 |
iHILIC®-(P) Classic,Guard Column,PEEK,20x2.1mm,5µm,200Å,3pk+coupler* |
|
P/N |
Product Name |
|
164.053.0520 |
iHILIC®-(P) Classic,HILIC Column,SS,50x3mm,5µm,200Å |
|
164.103.0520 |
iHILIC®-(P) Classic,HILIC Column,SS,100x3mm,5µm,200Å |
|
164.153.0520 |
iHILIC®-(P) Classic,HILIC Column,SS,150x3mm,5µm,200Å |
|
P/N |
Product Name |
|
180.051.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK-SS,50x1mm,5µm,200Å |
|
180.101.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK-SS,100x1mm,5µm,200Å |
|
180.151.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK-SS,150x1mm,5µm,200Å |
|
180.052.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK-SS,50x2.1mm,5µm,200Å |
|
180.102.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK-SS,100x2.1mm,5µm,200Å |
|
180.152.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK-SS,150x2.1mm,5µm,200Å |
|
180.252.0520 |
iHILIC®-(P) Classic,HILIC Column,PEEK-SS,250x2.1mm,5µm,200Å |
iHILIC®-Fusion色谱柱
|
P/N |
Product Name |
|
110.022.0110 |
iHILIC®-Fusion,HILIC Column,SS,20x2.1mm,1.8µm,100Å |
|
110.032.0110 |
iHILIC®-Fusion,HILIC Column,SS,30x2.1mm,1.8µm,100Å |
|
110.052.0110 |
iHILIC®-Fusion,HILIC Column,SS,50x2.1mm,1.8µm,100Å |
|
110.102.0110 |
iHILIC®-Fusion,HILIC Column,SS,100x2.1mm,1.8µm,100Å |
|
110.152.0110 |
iHILIC®-Fusion,HILIC Column,SS,150x2.1mm,1.8µm,100Å |
|
110.053.0110 |
iHILIC®-Fusion,HILIC Column,SS,50x3mm,1.8µm,100Å |
|
110.103.0110 |
iHILIC®-Fusion,HILIC Column,SS,100x3mm,1.8µm,100Å |
|
110.153.0110 |
iHILIC®-Fusion,HILIC Column,SS,150x3mm,1.8µm,100Å |
|
111.122.0110 |
iHILIC®-Fusion,Guard Column,SS,20x2.1mm,1.8µm,100Å,1pk |
|
111.222.0110 |
iHILIC®-Fusion,Guard Column,SS,20x2.1mm,1.8µm,100Å,2pk+coupler* |
iHILIC®-Fusion 色谱柱系列，是电荷修饰的的羟乙酰胺基 HILIC 柱：
|
P/N |
Product Name |
|
140.051.0110 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,50x1mm,1.8µm,100Å |
|
140.101.0110 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,100x1mm,1.8µm,100Å |
|
140.151.0110 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,150x1mm,1.8µm,100Å |
|
140.052.0110 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,50x2.1mm,1.8µm,100Å |
|
140.102.0110 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,100x2.1mm,1.8µm,100Å |
|
140.152.0110 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,150x2.1mm,1.8µm,100Å |
|
P/N |
Product Name |
|
110.022.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,20x2.1mm,3.5µm,100Å |
|
110.032.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,30x2.1mm,3.5µm,100Å |
|
110.052.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,50x2.1mm,3.5µm,100Å |
|
110.102.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,100x2.1mm,3.5µm,100Å |
|
110.152.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,150x2.1mm,3.5µm,100Å |
|
110.054.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,50x4.6mm,3.5µm,100Å |
|
110.104.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,100x4.6mm,3.5µm,100Å |
|
110.154.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,150x4.6mm,3.5µm,100Å |
|
110.254.0310 |
iHILIC®-Fusion,HILIC Column,PEEK,250x4.6mm,3.5µm,100Å |
|
110.022.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,20x2.1mm,5µm,100Å |
|
110.032.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,30x2.1mm,5µm,100Å |
|
110.052.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,50x2.1mm,5µm,100Å |
|
110.102.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,100x2.1mm,5µm,100Å |
|
110.152.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,150x2.1mm,5µm,100Å |
|
110.252.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,250x2.1mm,5µm,100Å |
|
110.054.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,50x4.6mm,5µm,100Å |
|
110.104.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,100x4.6mm,5µm,100Å |
|
110.154.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,150x4.6mm,5µm,100Å |
|
110.254.0510 |
iHILIC®-Fusion,HILIC Column,PEEK,250x4.6mm,5µm,100Å |
|
111.122.0510 |
iHILIC®-Fusion,Guard Column,PEEK,20x2.1mm,5µm,100Å,1pk |
|
111.322.0510 |
iHILIC®-Fusion,Guard Column,PEEK,20x2.1mm,5µm,100Å,3pk+coupler* |
|
P/N |
Product Name |
|
140.051.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,50x1mm,3.5µm,100Å |
|
140.101.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,100x1mm,3.5µm,100Å |
|
140.151.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,150x1mm,3.5µm,100Å |
|
140.052.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,50x2.1mm,3.5µm,100Å |
|
140.102.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,100x2.1mm,3.5µm,100Å |
|
140.152.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,150x2.1mm,3.5µm,100Å |
|
140.252.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,250x2.1mm,3.5µm,100Å |
|
140.054.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,50x4.6mm,3.5µm,100Å |
|
140.104.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,100x4.6mm,3.5µm,100Å |
|
140.154.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,150x4.6mm,3.5µm,100Å |
|
140.254.0310 |
iHILIC®-Fusion,HILIC Column,PEEK-SS,250x4.6mm,3.5µm,100Å |
iHILIC®-Fusion(+)系列色谱柱
iHILIC®-Fusion 色谱柱系列，是电荷修饰的的羟乙酰胺基 HILIC 柱：
|
P/N |
Product Name |
|
100.022.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,20x2.1mm,1.8µm,100Å |
|
100.032.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,30x2.1mm,1.8µm,100Å |
|
100.052.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,50x2.1mm,1.8µm,100Å |
|
100.102.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,100x2.1mm,1.8µm,100Å |
|
100.152.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,150x2.1mm,1.8µm,100Å |
|
100.053.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,50x3mm,1.8µm,100Å |
|
100.103.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,100x3mm,1.8µm,100Å |
|
100.153.0110 |
iHILIC®-Fusion(+),HILIC Column,SS,150x3mm,1.8µm,100Å |
|
101.122.0110 |
iHILIC®-Fusion(+),Guard Column,SS,20x2.1mm,1.8µm,100Å,1pk |
|
101.222.0110 |
iHILIC®-Fusion(+),Guard Column,SS,20x2.1mm,1.8µm,100Å,2pk+coupler* |
|
P/N |
Product Name |
|
150.051.0110 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,50x1mm,1.8µm,100Å |
|
150.101.0110 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,100x1mm,1.8µm,100Å |
|
150.151.0110 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,150x1mm,1.8µm,100Å |
|
150.052.0110 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,50x2.1mm,1.8µm,100Å |
|
150.102.0110 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,100x2.1mm,1.8µm,100Å |
|
150.152.0110 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,150x2.1mm,1.8µm,100Å |
|
P/N |
Product Name |
|
100.022.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,20x2.1mm,3.5µm,100Å |
|
100.032.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,30x2.1mm,3.5µm,100Å |
|
100.052.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,50x2.1mm,3.5µm,100Å |
|
100.102.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,100x2.1mm,3.5µm,100Å |
|
100.152.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,150x2.1mm,3.5µm,100Å |
|
100.054.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,50x4.6mm,3.5µm,100Å |
|
100.104.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,100x4.6mm,3.5µm,100Å |
|
100.154.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,150x4.6mm,3.5µm,100Å |
|
100.254.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK,250x4.6mm,3.5µm,100Å |
|
100.022.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,20x2.1mm,5µm,100Å |
|
100.032.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,30x2.1mm,5µm,100Å |
|
100.052.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,50x2.1mm,5µm,100Å |
|
100.102.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,100x2.1mm,5µm,100Å |
|
100.152.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,150x2.1mm,5µm,100Å |
|
100.252.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,250x2.1mm,5µm,100Å |
|
100.054.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,50x4.6mm,5µm,100Å |
|
100.104.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,100x4.6mm,5µm,100Å |
|
100.154.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,150x4.6mm,5µm,100Å |
|
100.254.0510 |
iHILIC®-Fusion(+),HILIC Column,PEEK,250x4.6mm,5µm,100Å |
|
101.122.0510 |
iHILIC®-Fusion(+),Guard Column,PEEK,20x2.1mm,5µm,100Å,1pk |
|
101.322.0510 |
iHILIC®-Fusion(+),Guard Column,PEEK,20x2.1mm,5µm,100Å,3pk+coupler* |
|
P/N |
Product Name |
|
150.051.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,50x1mm,3.5µm,100Å |
|
150.101.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,100x1mm,3.5µm,100Å |
|
150.151.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,150x1mm,3.5µm,100Å |
|
150.052.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,50x2.1mm,3.5µm,100Å |
|
150.102.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,100x2.1mm,3.5µm,100Å |
|
150.152.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,150x2.1mm,3.5µm,100Å |
|
150.252.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,250x2.1mm,3.5µm,100Å |
|
150.054.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,50x4.6mm,3.5µm,100Å |
|
150.104.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,100x4.6mm,3.5µm,100Å |
|
150.154.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,150x4.6mm,3.5µm,100Å |
|
150.254.0310 |
iHILIC®-Fusion(+),HILIC Column,PEEK-SS,250x4.6mm,3.5µm,100Å |
|
P/N |
Product Name |
|
104.022.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,20x2.1mm,3.5µm,100Å |
|
104.032.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,30x2.1mm,3.5µm,100Å |
|
104.052.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,50x2.1mm,3.5µm,100Å |
|
104.102.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,100x2.1mm,3.5µm,100Å |
|
104.152.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,150x2.1mm,3.5µm,100Å |
|
104.252.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,250x2.1mm,3.5µm,100Å |
|
104.053.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,50x3mm,3.5µm,100Å |
|
104.103.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,100x3mm,3.5µm,100Å |
|
104.153.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,150x3mm,3.5µm,100Å |
|
104.253.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,250x3mm,3.5µm,100Å |
|
104.054.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,50x4.6mm,3.5µm,100Å |
|
104.104.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,100x4.6mm,3.5µm,100Å |
|
104.154.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,150x4.6mm,3.5µm,100Å |
|
104.254.0310 |
iHILIC®-Fusion(+),HILIC Column,SS,250x4.6mm,3.5µm,100Å |
|
104.022.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,20x2.1mm,5µm,100Å |
|
104.032.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,30x2.1mm,5µm,100Å |
|
104.052.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,50x2.1mm,5µm,100Å |
|
104.102.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,100x2.1mm,5µm,100Å |
|
104.152.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,150x2.1mm,5µm,100Å |
|
104.252.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,250x2.1mm,5µm,100Å |
|
104.053.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,50x3mm,5µm,100Å |
|
104.103.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,100x3mm,5µm,100Å |
|
104.153.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,150x3mm,5µm,100Å |
|
104.253.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,250x3mm,5µm,100Å |
|
104.054.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,50x4.6mm,5µm,100Å |
|
104.104.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,100x4.6mm,5µm,100Å |
|
104.154.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,150x4.6mm,5µm,100Å |
|
104.254.0510 |
iHILIC®-Fusion(+),HILIC Column,SS,250x4.6mm,5µm,100Å |
iHILIC®-Fusion(P)系列色谱柱
iHILIC®-Fusion(P)
色谱柱系列，是电荷修饰的酰胺基HILIC色谱柱：
|
P/N |
Product Name |
|
130.022.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,20x2.1mm,5µm,200Å |
|
130.032.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,30x2.1mm,5µm,200Å |
|
130.052.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,50x2.1mm,5µm,200Å |
|
130.102.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,100x2.1mm,5µm,200Å |
|
130.152.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,150x2.1mm,5µm,200Å |
|
130.252.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,250x2.1mm,5µm,200Å |
|
130.054.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,50x4.6mm,5µm,200Å |
|
130.104.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,100x4.6mm,5µm,200Å |
|
130.154.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,150x4.6mm,5µm,200Å |
|
130.254.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK,250x4.6mm,5µm,200Å |
|
131.122.0520 |
iHILIC®-Fusion(P),Guard Column,PEEK,20x2.1mm,5µm,200Å,1pk |
|
131.322.0520 |
iHILIC®-Fusion(P),Guard Column,PEEK,20x2.1mm,5µm,200Å,3pk+coupler* |
|
P/N |
Product Name |
|
134.053.0520 |
iHILIC®-Fusion(P),HILIC Column,SS,50x3mm,5µm,200Å |
|
134.103.0520 |
iHILIC®-Fusion(P),HILIC Column,SS,100x3mm,5µm,200Å |
|
134.153.0520 |
iHILIC®-Fusion(P),HILIC Column,SS,150x3mm,5µm,200Å |
|
P/N |
Product Name |
|
170.051.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK-SS,50x1mm,5µm,200Å |
|
170.101.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK-SS,100x1mm,5µm,200Å |
|
170.151.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK-SS,150x1mm,5µm,200Å |
|
170.052.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK-SS,50x2.1mm,5µm,200Å |
|
170.102.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK-SS,100x2.1mm,5µm,200Å |
|
170.152.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK-SS,150x2.1mm,5µm,200Å |
|
170.252.0520 |
iHILIC®-Fusion(P),HILIC Column,PEEK-SS,250x2.1mm,5µm,200Å |
iSPE®-HILIC - SPE Cartridge and 96-well Plate for HILIC
iSPE-HILIC用HILIC设计用于纯化极性和亲水化合物。填充的固定相为电荷修饰的的羟乙基酰胺硅胶，其与中性、带正电和带负电的亲水官能团共价结合，分离机制基于亲水作用、氢键和弱静电作用的结合。具有独特的分离选择性和高分离效率，可用于糖肽、糖链、PSP毒素以及许多其他极性化合物的纯化
|
P/N |
Product Name |
|
200.001.0025 |
iSPE®-HILIC SPE Cartridge,1mL,25mg,50µm particle |
|
200.001.0050 |
iSPE®-HILIC SPE Cartridge,1mL,50mg,50µm particle |
|
200.001.0100 |
iSPE®-HILIC SPE Cartridge,1mL,100mg,50µm particle |
|
200.003.0100 |
iSPE®-HILIC SPE Cartridge,3mL,100mg,50µm particle |
|
200.003.0200 |
iSPE®-HILIC SPE Cartridge,3mL,200mg,50µm particle |
|
200.003.0500 |
iSPE®-HILIC SPE Cartridge,3mL,500mg,50µm particle |
|
200.006.0500 |
iSPE®-HILIC SPE Cartridge,6mL,500mg,50µm particle |
|
200.006.1000 |
iSPE®-HILIC SPE Cartridge,6mL,1 g,50µm particle |
|
200.006.2000 |
iSPE®-HILIC SPE Cartridge,6mL,2 g,50µm particle |
|
200.096.0025 |
iSPE®-HILIC SPE Cartridge,96-well,25mg,50µm particle |
|
200.096.0050 |
iSPE®-HILIC SPE Cartridge,96-well,50mg,50µm particle |
|
200.096.0100 |
iSPE®-HILIC SPE Cartridge,96-well,100mg,50µm particle |
|
200.096.0200 |
iSPE®-HILIC SPE Cartridge,96-well,200mg,50µm particle |
工具链接
判断一个化合物是否适合采用iHILIC进行分离和分析，最简便的办法可以查看化合物的logP值。
化合物的LogP是指脂水分配系数（Partition coefficient）的对数值，它用来描述化合物在油相（通常是正辛醇）和水相之间的分配平衡。具体来说，LogP是未解离的分子在油相与水相的分配系数P的对数值，其中P定义为化合物在有机相中的浓度与在水相中的浓度之比.LogP值的大小可以指示化合物的亲脂性，正LogP值表明化合物更倾向于存在于有机相中，而负LogP值则表明化合物更倾向于存在于水相中。
查找化合物的LogP值，您可以采用以下几种方法：
1. 数据库查询：
①[ChemSpider]网址：http://www.chemspider.com/
②[DrugBank]网址：http://www.drugbank.com/
③ [MolAid]网址：https://blog.csdn.net/qq_41753200/article/details/125796869
④ [ChemicalBook]网址：https://www.chemicalbook.com/
2. 软件预测：
① 使用化学绘图软件如[KingDraw](https://www.kingdraw.com/)，它不仅支持绘制结构式，还能够查询化合物信息，包括LogP值。
② ALOGPS：一个网页端工具，可以预测logP以及溶解度，网址为：http://146.107.217.178/web/alogps/。
③ Calculator Ultra：提供在线LogP计算器，网址为：https://www.calculatorultra.com/zh/tool/logp-partition-coefficient-calculator.html。
④ MarvinSketch：这款软件可以计算logP和logD，下载地址为：https://chemaxon.com/products/marvin/download。
⑤ 对于科研人员，ACD/Labs软件能预测化合物的LogP，适合没有实验数据时使用。
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